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1

Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia

Lynda M. Vrooman, Jeffrey G. Supko, Donna S. Neuberg, Barbara L. Asselin, Uma H. Athale, Luis Clavell, Kara M. Kelly, Caroline Laverdière, Bruno Michon, Marshall Schorin, Harvey J. Cohen, Stephen E. S

Journal:

Pediatric Blood & Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 135 KB

english, 2010

2

Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

Lynch, Thomas J., Bell, Daphne W., Sordella, Raffaella, Gurubhagavatula, Sarada, Okimoto, Ross A., Brannigan, Brian W., Harris, Patricia L., Haserlat, Sara M., Supko, Jeffrey G., Haluska, Frank G.

Journal:

Boston Medical and Surgical Journal

Année:

2004

Langue:

english

Fichier:

PDF, 442 KB

english, 2004

3

Ricolinostat plus lenalidomide, and dexamethasone in relapsed or refractory multiple myeloma: a multicentre phase 1b trial

Yee, Andrew J, Bensinger, William I, Supko, Jeffrey G, Voorhees, Peter M, Berdeja, Jesus G, Richardson, Paul G, Libby, Edward N, Wallace, Ellen E, Birrer, Nicole E, Burke, Jill N, Tamang, David L, Yan

Journal:

The Lancet Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 390 KB

english, 2016

4

Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma

Vogl, Dan T., Raje, Noopur, Jagannath, Sundar, Richardson, Paul, Hari, Parameswaran, Orlowski, Robert, Supko, Jeffrey G., Tamang, David, Yang, Min, Jones, Simon S., Wheeler, Catherine, Markelewicz, Ro

Journal:

Clinical Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 589 KB

english, 2017

5

A Phase I–II study of 96-hour infusional topotecan and paclitaxel for patients with recurrent müllerian tumors

Richard T. Penson, Jeffrey G. Supko, Michael V. Seiden, Arlan F. Fuller, Ross S. Berkowitz, Annekathryn Goodman, Susana M. Campos, Kimberley M. MacNeill, Sarah Cook, Ursula A. Matulonis

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 129 KB

english, 2001

6

A Phase I study of 9-nitrocamptothecin given concurrently with capecitabine in patients with refractory, metastatic solid tumors

M. Dror Michaelson, David P. Ryan, Charles S. Fuchs, Jeffrey G. Supko, Rocio Garcia-Carbonero, J. Paul Eder, Jeffrey W. Clark

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 83 KB

english, 2003

7

Phase II study of ecteinascidin 743 in heavily pretreated patients with recurrent osteosarcoma

Caroline Laverdiere, E. Anders Kolb, Jeffrey G. Supko, Richard Gorlick, Paul A. Meyers, Robert G. Maki, Leonard Wexler, George D. Demetri, John H. Healey, Andrew G. Huvos, Allen M. Goorin, Rochelle Ba

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 108 KB

english, 2003

8

Phase I trial and pharmacokinetics of escalating doses of paclitaxel and concurrent hyperfractionated radiotherapy with or without amifostine in patients with advanced head and neck carcinoma

Philip C. Amrein, John R. Clark, Jeffrey G. Supko, Richard L. Fabian, Chiu C. Wang, A. Dimitrios Colevas, Marshall R. Posner, Daniel G. Deschler, James W. Rocco, Dianne M. Finkelstein, James F. McInty

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 129 KB

english, 2005

9

Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid tumors

David P. Ryan, Leonard J. Appleman, Thomas Lynch, Jeffrey G. Supko, Panagiotis Fidias, Jeffrey W. Clark, Mayer Fishman, Andrew X. Zhu, Peter C. Enzinger, Oscar Kashala, James Cusack Jr., Joseph P. Ede

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 114 KB

english, 2006

10

A Phase I study of bortezomib plus irinotecan in patients with advanced solid tumors

David P. Ryan, Bert H. O'Neil, Jeffrey G. Supko, Carlo M. Rocha Lima, E. Claire Dees, Leonard J. Appleman, Jeffrey Clark, Phinos Fidias, Robert Z. Orlowski, Oscar Kashala, Joseph P. Eder, James C. Cus

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 278 KB

english, 2006

11

Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: Potentiation by Cox-2 inhibition

Jaime R. Merchan, Deepa R. Jayaram, Jeffrey G. Supko, Xiaoying He, Glenn J. Bubley, Vikas P. Sukhatme

Journal:

International Journal of Cancer

Année:

2005

Langue:

english

Fichier:

PDF, 354 KB

english, 2005

12

Characterization of a novel degradation product of 2,2′-dithiobis[N-isoleucylbenzamide], an inhibitor of HIV nucleocapsid protein zinc fingers

Lawrence R. Phillips, Louis Malspeis, Erin K. Tubbs, Jeffrey G. Supko

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2000

Langue:

english

Fichier:

PDF, 134 KB

english, 2000

13

Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors

Mark W. Kieran, Jeffrey G. Supko, Dana Wallace, Robert Fruscio, Tina Young Poussaint, Peter Phillips, Ian Pollack, Roger Packer, James M. Boyett, Susan Blaney, Anu Banerjee, Russ Geyer, Henry Friedman

Journal:

Pediatric Blood & Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 107 KB

english, 2009

14

Phase I clinical trial of the farnesyltransferase inhibitor BMS-214662 administered as a weekly 24

Joseph P. Eder, David P. Ryan, Leonard Appleman, Andrew X. Zhu, Thomas Puchalski, Xiaoying He, Daryl S. Sonnichsen, Michael Cooper, John Wright, Jeffrey W. Clark, Jeffrey G. Supko

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 276 KB

english, 2006

15

Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer

Jeffrey A. Meyerhardt, Jeffrey W. Clark, Jeffrey G. Supko, Joseph P. Eder, Shuji Ogino, Clinton F. Stewart, Ferdinando D’Amato, Janet Dancey, Peter C. Enzinger, Andrew X. Zhu, David P. Ryan, Craig C.

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 329 KB

english, 2007

16

A phase I clinical and pharmacokinetic study of the dolastatin analogue cemadotin administered as a 5-day continuous intravenous infusion

Jeffrey G. Supko, Thomas J. Lynch, Jeffrey W. Clark, Robert Fram, Lee F. Allen, Raja Velagapudi, Donald W. Kufe, Joseph Paul Eder Jr

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2000

Langue:

english

Fichier:

PDF, 154 KB

english, 2000

17

Plasma pharmacokinetics and bioavailability of 1-(2-chloroethyl)-3-sarcosinamide-1-nitrosourea after intravenous and oral administration to mice and dogs

Jeffrey G. Supko, Rocio Garcia-Carbonero, Thomas A. Puchalski, Louis Malspeis

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 126 KB

english, 2001

18

Phase I clinical trial of 7-cyanoquinocarcinol (DX-52-1) in adult patients with refractory solid malignancies

Craig A. Bunnell, Jeffrey G. Supko, Joseph Eder, Jeffrey W. Clark, Thomas J. Lynch, Donald W. Kufe, Lawrence N. Shulman

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 132 KB

english, 2001

19

Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study

Jaishri O. Blakeley, Jeffrey Olson, Stuart A. Grossman, Xiaoying He, Jon Weingart, Jeffrey G. Supko, For the New Approaches to Brain Tumor Therapy (NABTT) Consortium

Journal:

Journal of Neuro-Oncology

Année:

2009

Langue:

english

Fichier:

PDF, 394 KB

english, 2009

20

Intratumoral concentrations of imatinib after oral administration in patients with glioblastoma multiforme

Matthias Holdhoff, Jeffrey G. Supko, Gary L. Gallia, Christine L. Hann, David Bonekamp, Xiaobu Ye, Bing Cao, Alessandro Olivi, Stuart A. Grossman

Journal:

Journal of Neuro-Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 188 KB

english, 2010

21

Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma

Surasak Phuphanich, Jeffrey G. Supko, Kathryn A. Carson, Stuart A. Grossman, L. Burt Nabors, Tom Mikkelsen, Glenn Lesser, Steve Rosenfeld, Serena Desideri, Jeffrey J. Olson

Journal:

Journal of Neuro-Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 268 KB

english, 2010

22

A phase I/II trial and pharmacokinetic study of ixabepilone in adult patients with recurrent high-grade gliomas

David M. Peereboom, Jeffrey G. Supko, Kathryn A. Carson, Tracy Batchelor, Surasak Phuphanich, Glenn Lesser, Tom Mikkelson, Joy Fisher, Serena Desideri, Xiaoying He, Stuart A. Grossman, The New Approac

Journal:

Journal of Neuro-Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 187 KB

english, 2010

23

Erratum to: A phase I/II trial and pharmacokinetic study of ixabepilone in adult patients with recurrent high-grade gliomas

David M. Peereboom, Jeffrey G. Supko, Kathryn A. Carson, Tracy Batchelor, Surasak Phuphanich, Glenn Lesser, Tom Mikkelsen, Joy Fisher, Serena Desideri, Xiaoying He, Stuart A. Grossman, The New Approac

Journal:

Journal of Neuro-Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 86 KB

english, 2010

24

Cytotoxic chemotherapy: Advances in delivery, pharmacology, and testing

Roberto Ciordia, Jeffrey Supko, Michel Gatineau, Tracy Batchelor

Journal:

Current Oncology Reports

Année:

2000

Langue:

english

Fichier:

PDF, 392 KB

english, 2000

25

A Phase I Trial of Daily Oral 4′-N-Benzoyl-Staurosporine in Combination with Protracted Continuous Infusion 5-Fluorouracil in Patients with Advanced Solid Malignancies

Joseph P. Eder, Rocio Garcia-Carbonero, Jeffrey W. Clark, Jeffrey G. Supko, Thomas A. Puchalski, David P. Ryan, Pamela Deluca, Antoinette Wozniak, Angela Campbell, John Rothermel, Patricia LoRusso

Journal:

Investigational New Drugs

Année:

2004

Langue:

english

Fichier:

PDF, 139 KB

english, 2004

26

Prolonged stabilization of platinum-resistant ovarian cancer in a single patient consuming a fermented soy therapy

Amber Klein, Xiaoying He, Maria Roche, Allison Mallett, Linda Duska, Jeffrey G. Supko, Michael V. Seiden

Journal:

Gynecologic Oncology

Année:

2006

Langue:

english

Fichier:

PDF, 134 KB

english, 2006

27

Phase II study of liposomal doxorubicin and weekly paclitaxel for recurrent Müllerian tumors

Susanna M Campos, Ursula A Matulonis, Richard T Penson, Hang Lee, Ross S Berkowitz, Linda R Duska, Arlan F Fuller Jr., Kara S Wilson, Thomas A Puchalski, Jeffrey G Supko, Michael V Seiden

Journal:

Gynecologic Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 244 KB

english, 2003

28

P-348 A phase I trial of gemcitabine followed by flavopiridol in patients with solid tumors

Goffin, John, Appleman, Leonard, Ryan, David, Fidias, Panos, Lucca, Joan, Regan, Eileen, Dimitrios Colevas, A., Eder, Joseph Paul, Supko, Jeffrey, Shapiro, Geoffrey

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 369 KB

english, 2003

29

Trials of 9-Amino-20(S)-Camptothecin in Boston

JOSEPH P. EDER, ERIC RUBIN, RICHARD STONE, MARGARET BRYANT, GUANXIAN XU, JEFFREY SUPKO, NANCY KINCHLA, THOMAS LYNCH, SELWYN HURWITZ, DEE RODRIGUEZ, CHARLES SHAPIRO, DEBORAH TOPPMEYER, MICHAEL GROSSBAR

Journal:

Annals of the New York Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 437 KB

english, 1996

30

Dihydropyrimidine Dehydrogenase and Thymidylate Synthase Polymorphisms and Their Association with 5-Fluorouracil/Leucovorin Chemotherapy in Colorectal Cancer

Andrew X. Zhu, Thomas A. Puchalski, Vincent P. Stanton Jr, David P. Ryan, Jeffrey W. Clark, Steven Nesbitt, Olga Charlat, Patrick Kelly, Elaine Kreconus, Bruce A. Chabner, Jeffrey G. Supko

Journal:

Clinical Colorectal Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 286 KB

english, 2004

31

A phase II trial of oral gimatecan for recurrent glioblastoma

Hu, Jethro, Wen, Patrick Y., Abrey, Lauren E., Fadul, Camilo E., Drappatz, Jan, Salem, Nadia, Supko, Jeffrey G., Hochberg, Fred

Journal:

Journal of Neuro-Oncology

Année:

2013

Langue:

english

Fichier:

PDF, 200 KB

english, 2013

32

Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

Jeffrey G. Supko, Robert L. Hickman…

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 1.14 MB

english, 1995

33

Phase 1 study ofN1,N11-diethylnorspermine (DENSPM) in patients with advanced hepatocellular carcinoma

Goyal, Lipika, Supko, Jeffrey G., Berlin, Jordan, Blaszkowsky, Lawrence S., Carpenter, Amanda, Heuman, Douglas M., Hilderbrand, Sarah L., Stuart, Keith E., Cotler, Scott, Senzer, Neil N., Chan, Emily,

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 295 KB

english, 2013

34

Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target

Chen, Ting, Ozel, Duygu, Qiao, Yuan, Harbinski, Fred, Chen, Limo, Denoyelle, Séverine, He, Xiaoying, Zvereva, Nela, Supko, Jeffrey G, Chorev, Michael, Halperin, Jose A, Aktas, Bertal H

Journal:

Nature Chemical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 543 KB

english, 2011

35

Syntheses of 3-Chloro-7-[(Chlorocarbonyl)Methoxy]-4-Methylcoumarin

Phillips, Lawrence R., Supko, Jeffrey G., Wolfe, Tracy L., Malspeis, Louis

Journal:

Synthetic Communications

Année:

1996

Langue:

english

Fichier:

PDF, 353 KB

english, 1996

36

A Rapid Isocratic HPLC Assay of Suramin (NSC 34936) in Human Plasma

Supko, Jeffrey G., Malspeis, Louis

Journal:

Journal of Liquid Chromatography

Année:

1990

Langue:

english

Fichier:

PDF, 595 KB

english, 1990

37

A Reversed-Phase HPLC Method For Determining Camptothecin In Plasma With Specificity For the Intact Lactone Form of the Drug

Supko, Jeffrey G., Malspeis, Louis

Journal:

Journal of Liquid Chromatography

Année:

1991

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1991

38

Liquid Chromatographic Analysis of 9-Aminocamptothecin in Plasma Monitored by Fluorescence Induced upon Postcolumn Acidification

Supko, Jeffrey, Malspeis, Louis

Journal:

Journal of Liquid Chromatography & Related Technologies

Année:

1992

Langue:

english

Fichier:

PDF, 828 KB

english, 1992

39

HPLC Analysis of Merbarone (NSC 336628) in Plasma Using MG(II) Asamobile Phase Modifier

Malspeis, Louis, Supko, Jeffrey G.

Journal:

Journal of Liquid Chromatography

Année:

1990

Langue:

english

Fichier:

PDF, 880 KB

english, 1990

40

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

Gregory H. Bird, Navid Madani, Alisa F. Perry, Amy M. Princiotto, Jeffrey G. Supko, Xiaoying He, Evripidis Gavathiotis, Joseph G. Sodroski, Loren D. Walensky and Solomon H. Snyder

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2010

41

A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

Rosenfeld, Myrna R, Ye, Xiaobu, Supko, Jeffrey G, Desideri, Serena, Grossman, Stuart A, Brem, Steven, Mikkelson, Tom, Wang, Daniel, Chang, Yunyoung C, Hu, Janice, McAfee, Quentin, Fisher, Joy, Troxel,

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 797 KB

english, 2014

42

Metabolic Inhibition of Galectin-1-Binding Carbohydrates Accentuates Antitumor Immunity

Cedeno-Laurent, Filiberto, Opperman, Matthew J, Barthel, Steven R, Hays, Danielle, Schatton, Tobias, Zhan, Qian, He, Xiaoying, Matta, Khushi L, Supko, Jeffrey G, Frank, Markus H, Murphy, George F, Dim

Journal:

The Journal of Investigative Dermatology

Année:

2012

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2012

43

Case 11-2006

Cabot, Richard C., Harris, Nancy Lee, Shepard, Jo-Anne O., Ebeling, Sally H., Peters, Christine C., Krasner, Carolyn N., Roche, Maria, Horowitz, Neil S., Supko, Jeffrey G., Lee, Susanna I., Oliva, Est

Journal:

Boston Medical and Surgical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 523 KB

english, 2006

44

Phase I study of iniparib concurrent with monthly or continuous temozolomide dosing schedules in patients with newly diagnosed malignant gliomas

Blakeley, Jaishri O., Grossman, Stuart A., Mikkelsen, Tom, Rosenfeld, Myrna R., Peereboom, David, Nabors, L. Burt, Chi, Andrew S., Emmons, Gary, Ribas, Ignacio Garcia, Supko, Jeffrey G., Desideri, Ser

Journal:

Journal of Neuro-Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 371 KB

english, 2015

45

Disappearance of Endogenous Luteinizing Hormone Is Prolonged in Postmenopausal Women 1

Sharpless, Julie L., Supko, Jeffrey G., Martin, Kathryn A., Hall, Janet E.

Journal:

Journal of Clinical Endocrinology & Metabolism

Année:

1999

Langue:

english

Fichier:

PDF, 175 KB

english, 1999

46

Intravenous pegylated asparaginase versus intramuscular native Escherichia coli l-asparaginase in newly diagnosed childhood acute lymphoblastic leukaemia (DFCI 05-001): a randomised, open-label phase 3 trial

Place, Andrew E, Stevenson, Kristen E, Vrooman, Lynda M, Harris, Marian H, Hunt, Sarah K, O'Brien, Jane E, Supko, Jeffrey G, Asselin, Barbara L, Athale, Uma H, Clavell, Luis A, Cole, Peter D, Kelly, K

Journal:

The Lancet Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 490 KB

english, 2015

47

Exposure to Phytoestrogens in the Perinatal Period Affects Androgen Secretion by Testicular Leydig Cells in the Adult Rat

Akingbemi, Benson T., Braden, Tim D., Kemppainen, Barbara W., Hancock, Karen D., Sherrill, Jessica D., Cook, Sarah J., He, Xiaoying, Supko, Jeffrey G.

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 599 KB

english, 2007

48

Pharmacokinetic Factors Contribute to the Inverse Relationship between Luteinizing Hormone and Body Mass Index in Polycystic Ovarian Syndrome

Srouji, Serene S., Pagán, Yanira L., D’Amato, Fernando, Dabela, Amsalu, Jimenez, Yarisie, Supko, Jeffrey G., Hall, Janet E.

Journal:

Journal of Clinical Endocrinology & Metabolism

Année:

2007

Langue:

english

Fichier:

PDF, 120 KB

english, 2007

49

Concurrent Determination of Merbarone and Its Urinary Metabolites by Reversed-Phase HPLC with Precolumn Phenolic Acetylation

Supko, Jeffrey G., Malspeis, Louis

Journal:

Journal of Liquid Chromatography

Année:

1991

Langue:

english

Fichier:

PDF, 1002 KB

english, 1991

50

A Phase I Study of Erlotinib and Hydroxychloroquine in Advanced Non–Small-Cell Lung Cancer

Goldberg, Sarah B., Supko, Jeffrey G., Neal, Joel W., Muzikansky, Alona, Digumarthy, Subba, Fidias, Panos, Temel, Jennifer S., Heist, Rebecca S., Shaw, Alice T., McCarthy, Patricia O., Lynch, Thomas J

Journal:

Journal of Thoracic Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2012